Exhibit 21

SUBSIDIARIES OF OPKO HEALTH, INC.

听

NAME			听听			JURISDICTION OF INCORPORATION
OPKO Instrumentation, LLC			听听			Delaware
OPKO Pharmaceuticals, LLC			听听			Delaware
OPKO Diagnostics, LLC			听听			Delaware
ModeX Therapeutics, Inc.			听听			Delaware
OPKO Chile, S.A.			听听			Chile
Arama Natural Products Distribuidora, Ltda						Chile
Pharmacos Exakta S.A. de C.V.			听听			Mexico
FineTech Pharmaceutical Ltd			听听			Israel
男人宫殿 Europe, S.L.			听听			Spain
OPKO Biologics, Ltd						Israel
OPKO Ireland Global Holdings, Ltd						Ireland
OPKO Ireland, Ltd						Ireland
OPKO Canada Corp, ULC						Canada
OPKO Renal, LLC						Canada
Curna, Inc.						Delaware
BioReference Laboratories, Inc.						New Jersey
EirGen Pharma Limited						Ireland
Transition Therapeutics, Inc.						Canada