˹

Form: S-8

Initial registration statement for securities to be offered to employees pursuant to employee benefit plans

May 15, 2023

As filed with the Securities and Exchange Commission on May 15, 2023

Registration No. 333-_____



UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM S-8

REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
—ĔĔĔĔĔĔĔĔĔĔ
˹.
(Exact name of registrant as specified in its charter)

Delaware

75-2402409

(State or other jurisdiction of incorporation or organization)

(I.R.S. Employer Identification No.)

—ĔĔĔĔĔĔĔĔĔĔ

4400 Biscayne Blvd.

Miami, Florida

(Address of Principal Executive Offices)

33137

(Zip Code)

˹. 2016 Equity Incentive Plan

(Full title of the plan)

Camielle Green

Associate General Counsel, Secretary

˹.

4400 Biscayne Boulevard

Miami, Florida 33137

(305) 575-4100

(Telephone number, including area code, of agent for service)

Copies to:

Robert L. Grossman, Esq.

Drew M. Altman, Esq.

Greenberg Traurig, P.A.

333 S.E. 2nd Avenue

Suite 4400

Miami, Florida 33131

(305) 579-0500

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company” and “emerging growth company” in Rule 12b-2 of the Exchange Act:

Large accelerated filer

Accelerated Filer

Non-accelerated filer

Smaller reporting company

Emerging growth company

If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.☐




STATEMENT OF INCORPORATION BY REFERENCE

This Registration Statement on Form S-8 is being filed by ˹., a Delaware corporation (the “Registrant”), for the purpose of registering a total of 30,000,000 additional shares of its common stock, par value $0.01 per share (“Common Stock”), issuable under the ˹. 2016 Equity Incentive Plan (as amended, the “Plan”).

Pursuant to Instruction E of Form S-8, the contents of the Registrant’s prior registration statement on Form S-8 registering shares of Common Stock under the Plan (File No. 333-211209) (the
Prior Registration Statement”) is hereby incorporated by reference herein, and the information required by Form S-8 is omitted, except that the provisions contained in Part II of the Prior Registration Statement are modified as set forth in this Registration Statement


PART II

Item 3. Incorporation of Documents by Reference.

The following documents, which have been filed by the Registrant with the Commission are incorporated herein by reference:

(a)

(b)

(c)

(d)

Current Reports on Form 8-K, filed with the Commission on , , and ; and

(e)

, including any amendments or reports filed for the purpose of updating that description, including the description of the Common Stock filed as .

Additionally, all documents subsequently filed by the Registrant pursuant to Sections 13(a), 13(c), 14 and 15(d) of the Exchange Act of 1934, as amended (not including any information furnished under Items 2.02, 7.01 or 9.01 of Form 8-K, which information is not incorporated by reference herein), prior to the filing of a post-effective amendment which indicates that all securities offered hereby have been sold or which deregisters all securities then remaining unsold, shall be deemed to be incorporated herein by reference and to be a part of this Registration Statement from the date of filing of such documents. Any statement contained in a document incorporated herein by reference will be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained herein, or in a subsequently filed document incorporated herein by reference, modifies or supersedes the statement. Any statement modified or superseded will not be deemed, except as modified or superseded, to constitute a part of this Registration Statement.

Item 8.Exhibits.

The following are the exhibits required by Item 601 of Regulation S-K:

Exhibit No.

Description

5.1

Opinion of Greenberg Traurig, LLP

23.1

Consent of Ernst & Young LLP, Independent Registered Public Accounting Firm.

23.2

Consent of Greenberg Traurig, LLP (included in Exhibit 5.1).

24.1

Power of Attorney (included on signature pages hereto).

107.1

Filing Fee Table


SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City Miami, State of Florida, on May 15, 2023.

˹.

By:

/s/ Steven D. Rubin

Date: May 15, 2023

Name:

Steven D. Rubin

Title:

Executive Vice President-Administration


POWER OF ATTORNEY

KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Steven D. Rubin with full power to act as such person’s true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for such person and in such person’s name, place and stead, in any and all capacities, to sign this Registration Statement, and any and all amendments thereto (including post-effective amendments), and to file the same, with exhibits thereto, and all other documents in connection therewith, with the Securities and Exchange Commission, granting unto saidattorney-in-factand agent or his substitute, may lawfully do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the date indicated.

Signature

Title

Date

/s/Phillip Frost, M.D.

Chief Executive Officer and Chairman of the Board

May 15, 2023

Phillip Frost, M.D.

(Principal Executive Officer)

/s/ Jane H. Hsiao, Ph.D. Vice Chairman of the Board and Chief Technical Officer May 15, 2023

Jane H. Hsiao, Ph.D.

/s/ Steven D. Rubin Executive Vice President-Administration and Director May 15, 2023

Steven D. Rubin

/s/ Elias A. Zerhouni, M.D. Vice Chairman of the Board and President May 15, 2023

Elias A. Zerhouni, M.D.

/s/ Gary J. Nabel, M.D., Ph.D. Director and Chief Innovation Officer May 15, 2023

Gary J. Nabel, M.D., Ph.D.

/s/ Alexis Borisy Director May 15, 2023

Alexis Borisy

/s/Richard M. Krasno, Ph.D. Director May 15, 2023

Richard M. Krasno, Ph.D.

/s/ Prem A. Lachman Director May 15, 2023

Prem A. Lachman

/s/Roger J. Medel, M.D. Director May 15, 2023

Roger J. Medel, M.D.

/s/John A. Paganelli Director May 15, 2023

John A. Paganelli

/s/ Richard C. Pfenniger, Jr. Director May 15, 2023

Richard C. Pfenniger, Jr.

/s/Alice Lin-Tsing Yu, M.D., Ph.D. Director May 15, 2023

Alice Lin-Tsing Yu, M.D., Ph.D.